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SP 600125, negative control
CAS No. 54642-23-8
SP 600125, negative control( —— )
Catalog No. M35021 CAS No. 54642-23-8
SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 37 | In Stock |
|
| 10MG | 61 | In Stock |
|
| 25MG | 118 | In Stock |
|
| 50MG | 178 | In Stock |
|
| 100MG | 258 | In Stock |
|
| 500MG | 626 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSP 600125, negative control
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NoteResearch use only, not for human use.
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Brief DescriptionSP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125.
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DescriptionSP 600125, negative control (SPM1) is an alkyl derivative of pyrazoloanthrone, which can be used as a negative control for SP600125 (HY-12041).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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TargetJNK
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RecptorJNK
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Research Area——
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Indication——
Chemical Information
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CAS Number54642-23-8
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Formula Weight234.25
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Molecular FormulaC15H10N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 10 mg/mL (42.69 mM; Ultrasonic (<70°C)
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SMILESO=C1C=2C=3C(C=4C1=CC=CC4)=NN(C)C3C=CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Tanzisertib
Tanzisertib (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.Tanzisertib (CC-930) inhibits the formation of phospho-cJun in human PBMC stimulated by phorbol-12-myristate-13-acetate and phytohemeagglutinin (IC50=1 μM)[1] and it blocks the JNK pathway that is activated by pro-fibrotic cytokines in systemic sclerosis.
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Caffeic Acid
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.
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JNK-IN-11
JNK-IN-11 (compound 1) is a potent inhibitor of JNK, with IC50 values of 2.2 μM, 21.4 μM, and 1.8 μM for JNK1, JNK2, and JNK3, respectively, showing potential for Alzheimer's and Parkinson's disease research.
